Wednesday, May 7, 2008

A Parametric Model for Ordinal Response Data, with Application to Estimating Age-specific Reference Intervals

by Patrick Royston (1)
(1) MRC Clinical Trials Unit, 222 Euston Road, NW1 2DA, London, UK

Abstract
A model for ordinal response data based on an underlying (but unobserved) Normal distribution is proposed. The model is particularly useful for highly discrete data with a large proportion of zero values. It is applied to the estimation of age-specific reference intervals in two substantive example datasets.

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